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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Antipyrine
Research Papers that Mention the Interaction
“A highly significant correlation (p < 0.001) was found between Phenazone clearance and the prothrombin time, albumin , γ-globulin, factor V, antithrombin III, fibrinogen and total bilirubin.”
Identification of Patients with Impaired Hepatic Drug Metabolism Using a Limited Sampling Procedure for Estimation of Phenazone (Antipyrine) Pharmacokinetic Parameters“Significant negative correlation was observed between antipyrine half‐life and albumin concentration in patients with gastric carcinoma (r = −0.626, P < 0.05).”
“Significant negative correlation was observed between antipyrine half-life and albumin concentration (r = -0.786, P less than 0.01).”
“It was found that sensibilization of albumin increased the half-time (T1/2), AUC and decreased the total body clearance (Clt) of antipyrine and the renal clearance (Clr) of metabolites in urine.”
[Effects of zixoryn on pharmacokinetics of antipyrine in intact and sensitized guinea pigs].“The clearance of antipyrine , a compound not bound to albumin or alpha-1 acid glycoprotein, increased 28% in the presence of albumin but was not altered in the presence of alpha-1 acid glycoprotein.”
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