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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Albumin
drug:
Aldosterone
Research Papers that Mention the Interaction
“Intravital multiphoton imaging confirmed that aldosterone caused damage of the glomerular endothelial glycocalyx and increased the glomerular sieving coefficient for albumin.”
Aldosterone induces albuminuria via matrix metalloproteinase-dependent damage of the endothelial glycocalyx.“Treatment with midodrine and albumin was associated with a slight but significant decrease in plasma renin activity and aldosterone compared to placebo (renin -4.3 vs. 0.1 ng/ml.h, p < 0.001; aldosterone -38 vs. 6 ng/dl, p = 0.02, at week 48 vs. baseline).”
“Sandberg, Slaunwhite and Carter (… an appreciable binding of aldosterone in diluted … dialyzed against albumin at 40 C. The aldosterone was readily displaced from the binding protein by the addition of cortisol, while … binding under similar conditions was not significantly reduced by the addition of physiological amounts of aldosterone (9).”
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