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Last Updated: 3 years ago

Possible Interaction: Albumin and 2-Amino-1-Methyl-6-Phenylimidazo(4,5-B)Pyridine

supplement:

Albumin

drug:

2-Amino-1-Methyl-6-Phenylimidazo(4,5-B)Pyridine

Research Papers that Mention the Interaction

“Genotoxic N-oxidized metabolites of PhIP react with the Cys34 of albumin (Alb) to form a sulfinamide adduct, a biomarker of the biologically effective dose.”
Biomonitoring an albumin adduct of the cooked meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in humans
Carcinogenesis  •  2018  |  View Paper
“We previously identified an adduct of PhIP formed at the Cys(34) residue of human serum albumin following reaction of albumin with the genotoxic metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (HONH-PhIP).”
Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.
Chemical research in toxicology  •  2015  |  View Paper