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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
supplement:
Vitamin B 6
Research Papers that Mention the Interaction
“Mutation of Arg-277 to Ala increases the K(m) for PLP by 270-fold compared to that of wild-type ODC while reducing k(cat) by only 2-fold at pH 8.”
Role of Arg-277 in the binding of pyridoxal 5'-phosphate to Trypanosoma brucei ornithine decarboxylase.“Both alanine and glutamate activities decreased steadily in the presence of pyridoxal 5'-phosphate.”
“The intestinal cell alanine accumulation is reduced by pyridoxine , and cell Na and K concentrations in the presence of pyridoxine were not different from those of controls.”
“Oxidation of L-alanine by the organism was inhibited by GHA, and this inhibition was partially antagonized by PyP and by L-alanine.”
“Both Al3+ and pyridoxal are specifically required because replacing these by other cations or by other vitamin B6 derivatives greatly lowers the formation of alanine.”
Non-enzymic β-decarboxylation of aspartic acid“ Pyridoxal phosphate partially replaced the L-alanine.”
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