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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alanine and Valine





Research Papers that Mention the Interaction

The exchange of valine 738 to alanine was accompanied by a ~50% reduction in receptor efficacy.
BMC Neuroscience  •  2005  |  View Paper
Substitution of alanine for valine at the corresponding position in the δ and α subunit prolongs the burst duration four‐ and eightfold, respectively.
Human mutation  •  2016  |  View Paper
Substitution of the valine and histidine residues at positions 4 and 9 with tryptophan and alanine , respectively, resulted in the increase of enthalpy of the interaction, thereby increasing the binding affinity for C3.
Journal of Biological Chemistry  •  2004  |  View Paper
A-S of isoleucine, leucine and valine showed significant positive correlation to that of alanine (r = 0.59, r = 0.89, r = 0.77, respectively, during exercise, and r = 0.57, r = 0.65, r = 0.72, respectively, during pacing).
Japanese circulation journal  •  1993  |  View Paper
Similarly, replacement of a P4 valine with alanine severely reduced cleavage efficiency, whereas its replacement with lysine abolished cleavage.
The Journal of biological chemistry  •  2002  |  View Paper
Valine uptake was inhibited by leucine and alpha-aminoisobutyric acid and by high concentrations of L-alanine , L-lysine, cycloleucine, L-glutamine, and L-methionine, but not by 2-(methyl-amino)-isobutyric acid.
Journal of animal science  •  2000  |  View Paper
A 20-fold excess of unlabeled leucine, isoleucine, methionine, valine , alanine, lysine, histidine, phenylalanine, and glutamine inhibited uptake of leucine and phenylalanine, and six of these amino acids inhibited uptake of alanine , by more than 50% both in the presence and absence of a potassium ion gradient.
Biochimica et biophysica acta  •  1993  |  View Paper
In addition, both 2-aminoendobicyclo [2,2,1]heptane-2-carboxylic acid (Ki approximately 1.0 mM) and L-valine (Ki approximately 0.10 mM) appeared to inhibit Na+-dependent transport of alanine and BCO competitively.
The Journal of biological chemistry  •  1985  |  View Paper
Isoleucine and valine , by contrast, enhanced production of both alanine and glutamine in these tissues.
The American journal of physiology  •  1980  |  View Paper
Aspartate, cysteine, leucine, valine , methionine, isoleucine, serine, theronine, and glycine increased significantly the formation and release of alanine from muscle.
The Journal of biological chemistry  •  1976  |  View Paper
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