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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Alanine and Thyrotropin-Releasing Hormone

Research Papers that Mention the Interaction

In EL1, conversion of Tyr93 to Ala resulted in more than 20-fold decrease in affinity for MeTRH.
In EL2 and the top portion of the …, conversion of Tyr181 to Phe, Tyr188 to Ala , and Phe199 to Ala resulted in … ( > 100-fold) decrease in affinity for MeTRH , and conversion of Tyr 188 to Phe and Phe196 to … an agonist-specific 4- to 5-fold decrease in affinity.
In EL3, conversion of Asn289 to Ala and of Ser290 to Ala caused a large ( > 100-fold) decrease in affinity for MeTRH.
Molecular endocrinology  •  1995  |  View Paper