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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
drug:
Somatropin
Research Papers that Mention the Interaction
“Replacement of potential Zn2+ ligands (His18, His21, and Glu174) in hGH with alanine weakened both Zn2+ binding and hGH dimer formation.”
Dimerization of human growth hormone by zinc.“Fasting serum concentrations of alanine , glycine, arginine, and tryptophan were also significantly elevated (P less than .01) with hGH treatment; ornithine, tyrosine, lysine, methionine, and phenylalanine showed lesser elevations (P less than 0.5), whereas threonine decreased significantly (P less than 0.01).”
“These infusions did not lower basal HGH or improve its glucose suppressibility in untreated PCM, excluding a feedback relationship between HGH and alanine.”
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