supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
supplement:
Alanine
supplement:
Polypeptides
Research Papers that Mention the Interaction
“Substitution of a single residue in β1, Cys-162, to alanine prevented palmitoylation, reduced the level of β1 polypeptides at the plasma membrane, and reduced the extent of β1-regulated intramembrane proteolysis, suggesting that the plasma membrane is the site of β1 proteolytic processing.”
Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis“ Alanine and threonine residues added to the C terminus of stalled nascent chains (CAT tails) increase degradation of such polypeptides by promoting their ubiquitylation by Ltn1 or by acting as degrons off the ribosome.”
CAT tails drive degradation of stalled polypeptides on and off the ribosome“The clouding point (CP) of random copolypeptides can be tuned by altering the alanine content and overall MW.”
“In chlorosomes isolated from resting cultures supplied with ALA the amounts of all of the polypeptides increased only slightly, if at all.”
“By contrast, the individual replacement of cysteines 57 or 83 by alanine , as well as the simultaneous mutation of cysteines 83 and 87, significantly reduced the ability of Gag polypeptides to produce extracellular particles.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback