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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
drug:
Phenformin
Research Papers that Mention the Interaction
“During the baseline … arterial concentration of alanine and the hepatic venous concentration ratios of alanine: pyruvate andβ-hydroxybutyrate: acetoacetate were significantly increased with phenformin treatment, while the balances of carbon dioxide and glucose and the fractional extraction of alanine were decreased compared to the values obtained in untreated subjects.”
Effect of phenformin on hepatic balances of gluconeogenic substrates in man“Gluconeogenesis from lactate, pyruvate, alanine and glycerol by isolated perfused guinea-pig liver is inhibited to various degrees by phenethylbiguanide.”
Phenethylbiguanide and the inhibition of hepatic gluconeogenesis in the guinea pig.
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