Possible Interaction: Alanine and Oleic Acid

“Increasing circulating levels of BCAA and oleic acid may have great potential to increase the syntheses of glutamate, glutamine, aspartate, alanine , and asparagine by lactating mammary glands, thereby leading to enhanced production of milk for suckling neonates.”

“However, … oleic acid on the … and L-alanine appeared to be related to the enhanced collapse of the Na+ gradient rather than a direct effect on the carrier systems … solutes when measured in the absence of a Na+ gradient ([Na+]i = [Na+]o) was not affected by oleic acid.”

“Treatment of … vesicles with oleic acid also inhibited other carrier-mediated transport systems as well, such as the H+ gradient-… transport of glycylsarcosine and the Na+ gradient-driven transport of D-glucose and L-alanine , whereas it did not affect the permeability … L-glucose, a non-carrier-mediated process.”