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Last Updated: 2 years ago

Possible Interaction: Alanine and Methionine

supplement:

Alanine

supplement:

Methionine

Research Papers that Mention the Interaction

Mutations of the methionine (M) or threonine (T) to alanine (A) reduced the dominant positive effect, while mutation of the tyrosine (Y) to either A or phenylalanine (F) completely abolished the dominant positive effect.
Gene  •  2015  |  View Paper
Substituting all four methionines to alanine significantly reduced the formation of DA-mediated soluble oligomers.
Free radical biology & medicine  •  2009  |  View Paper
Via alanine , isoleucine, L-serine dehydratase/L-threonine deaminase and other proteins, AgNP-cit altered the metabolism of glycine, serine and threonine, cysteine and methionine , affecting oxidation and deamination, and ultimately leading to liver damage.
Nanotoxicology  •  2018  |  View Paper
Plasma alanine concentration was linearly increased as DLM or 2‐hydroxy‐4‐(methylthio) butanoic acid (HMTBA) supplementation level increased.
Animal science journal = Nihon chikusan Gakkaiho  •  2017  |  View Paper
The substitution of methionine with glycine, threonine, or alanine caused a complete loss of the neotropic activity of the peptide.
Izvestiia Akademii nauk. Seriia biologicheskaia  •  2005  |  View Paper
A 20-fold excess of unlabeled leucine, isoleucine, methionine , valine, alanine, lysine, histidine, phenylalanine, and glutamine inhibited uptake of leucine and phenylalanine, and six of these amino acids inhibited uptake of alanine , by more than 50% both in the presence and absence of a potassium ion gradient.
Biochimica et biophysica acta  •  1993  |  View Paper
Methionine is an effective inhibitor of both Na‐independent uptake mechanisms for alanine.
The Journal of physiology  •  1981  |  View Paper
Uptake of Leu and of Ala from the tetrapeptides was strongly inhibited by Met , as was uptake of these amino acids from free solution.
Biochimica et biophysica acta  •  1979  |  View Paper
Kinetic studies showed that ethionine, norleucine, and alanine are also competitive inhibitors of methionine uptake.
l -Ethionine and l -norleucine, as well as a number of neutral, nonpolar amino acids (leucine, isoleucine, valine, and alanine ) also inhibit methionine uptake.
Experimental parasitology  •  1977  |  View Paper
Other essential amino acids such as l-lysine, l-histidine, and l-methionine at 2 mM concentrations were also significantly inhibited by 40 mM l-Ala.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1976  |  View Paper
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