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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Mutation of Ser‐318 to alanine abrogates the inhibitory effect of leptin on insulin‐induced Irs1 tyrosine phosphorylation and glucose uptake in L6 myoblasts.”
Leptin down‐regulates insulin action through phosphorylation of serine‐318 in insulin receptor substrate 1“In the ROC analysis, the combination of leptin and alanine showed a high IR discrimination value in the whole cohort (area under curve, AUCALL=0.87), as well as in boys (AUCM=0.84) and girls (AUCF=0.91) when considered separately.”
“ConclusionMaternal supplementation of ALA in normal and protein-restricted diets modulates n-3 PUFA levels, cholesterol, leptin levels and also adipose growth in the suckling offspring.”
Maternal supplementation of α-linolenic acid in normal and protein-restricted diets modulate lipid metabolism, adipose tissue growth and leptin levels in the suckling offspring“ Leptin or insulin alone decreased (p < 0.05) the activation of hepatic glucose, L‐lactate and urea production from L‐alanine.”
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