Possible Interaction: Alanine and Inosine

“In ischemic hearts metabolizing either [3-13C]pyruvate or [1-13C]glucose, 1 mM INO increased both total and 13C-labeled alanine content; lactate content was unaffected.”

“The lag period also dissipated when inosine was supplemented with the co-germinator alanine.”

“These mutant spores, however, germinated efficiently when inosine was supplemented with alanine.”

“Stimulation of germination in L-alanine by limiting concentrations of inosine and stimulation of germination in inosine by low concentrations of L-alanine were still detectable in these mutants, suggesting that such stimulation is not dependent on complete functionality of both these germination loci.”

“Stimulation of germination in l-alanine by limiting concentrations of inosine and stimulation of germination in inosine by low concentrations of l-alanine were still detectable in these mutants, suggesting that such stimulation is not dependent on complete functionality of both these germination loci.”

“The calcium requirement itself was remarkably diminished under the condition in which l‐alanine and a certain purine nucleoside analog, adenosine or inosine , coexisted.”

“The highest level of cooperative action of L-alanine and inosine on the germination was observed when they were present in a ratio 1:1.”

“The effectiveness of some amino acids in permitting germination in inosine decreases in the order L-alanine , L-α-amino-n-butyric acid, L-isoleucine, glycine, L-valine, L-serine, L-leucine.”