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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Alanine
drug:
Hydrocortisone
Research Papers that Mention the Interaction
“Galactose and alanine enhanced sodium and water absorption and further significant increases occurred in the presence of hydrocortisone.”
Inter-relationships between the absorptions of hydrocortisone, sodium, water and actively transported organic solutes in the human jejunum“During cortisol , but not during saline infusion, the rate and percentage of leucine nitrogen going to alanine increased (P less than 0.05).”
“Thus, an increase in plasma cortisol within the physiologic range increases proteolysis and the de novo synthesis of alanine , a potential gluconeogenic substrate.”
“In rats varying in age from 4 days to 24 weeks, treatment with 1 mg of cortisol for 4 days resulted in significant increases in hepatic alanine transaminase activity.”
“In the presence of cortisol , preferential uptake of alanine into glycogen persisted throughout the 22 h of incubation, and equilibrium was not reached.”
Stimulation of gluconeogenesis by cortisol in fetal rat liver in organ culture.“A single … of hydrocortisone to intact rabbits increases … incorporation of [14C] alanine into proteins of the brain and liver tissue homogenates and soluble fractions as well as in blood plasma proteins … reduces the label incorporation into the brain tissue proteins and reduces its incorporation into the blood plasma proteins.”
“When this high-protein diet was fed, treatment with cortisol (4 mg/kg) increased alanine transaminase activity fourfold.”
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