Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 months ago

Possible Interaction: Alanine and Halofantrine



Research Papers that Mention the Interaction

The half-maximal inhibitory concentration (IC50) for block of wild-type (WT) HERG was … μM. As we reported previously for other HERG channel blockers, the potency of halofantrine was reduced … to Ala of aromatic residues (Y652, F656) located in the S6 … a Val (V625) located in the pore helix.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper