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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
drug:
Halofantrine
Research Papers that Mention the Interaction
“The half-maximal inhibitory concentration (IC50) for block of wild-type (WT) HERG was … μM. As we reported previously for other HERG channel blockers, the potency of halofantrine was reduced … to Ala of aromatic residues (Y652, F656) located in the S6 … a Val (V625) located in the pore helix.”
Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine
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