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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
supplement:
Guanidines
Research Papers that Mention the Interaction
“ Guanidine treatment at pH 4.5 decreased the reversible stabilities of Gly137- ->Ala , Gly139-->Ala and Gly137/Gly139-->Ala/Ala glucoamylases at infinite dilution while not changing those of Gly251-->Ala and Gly383-->Ala glucoamylases, which is, in general, opposite to what occurred with thermoinactivation.”
Effect of replacing helical glycine residues with alanines on reversible and irreversible stability and production of Aspergillus awamori glucoamylase.“The exchange of Thr29 and Ser39 for Ala leads to significantly less aggregation in guanidine HCl than is observed for wild-type LDH.”
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