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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
drug:
Dofetilide
Research Papers that Mention the Interaction
“… alanine of three residues near the pore helix (… Val659) reduced channel sensitivity to block by dofetilide and E-4031, effects identical with those reported previously for two other methanesulfonanilides, (+)- N -[1′ -(6-cyano-…(R)-hydroxyspiro(2H -1-benzopyran-2,4′ -piperidin)-6-yl]-methanesulfonamide] monohydrochloride (MK-499) and ibutilide.”
Molecular Determinants of hERG Channel Block
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