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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Alanine
drug:
Dinoprostone
Research Papers that Mention the Interaction
“ PGE2 , LTB4 synthesis and ALOX5 expression was suppressed by LA, GLA, ALA and DHA; whereas AA, EPA and 5-FU enhanced PGE2 but paradoxically AA decreased and EPA and 5-FU enhanced LTB4 synthesis in RKO cells.”
Growth Inhibitory Effect of Polyunsaturated Fatty Acids (PUFAs) on Colon Cancer Cells via Their Growth Inhibitory Metabolites and Fatty Acid Composition Changes“In contrast, change of these three residues to alanine completely blocks the induction of CCR7 by PGE2.”
“It was found that a combination of EPA + DCHA (6:4), DCHA and ALA caused significant reduction in synthesis of PGE2 (10.1-87.8%) and PGF2 alpha (14.0-54.6%) at the four dose levels studied.”
“Supplementation with ALA increased both PGE2 and PGF2α concentrations in the spent media (P ≤ 0.05).”
Effect of α-linolenic acid on oocyte maturation and embryo development of prepubertal sheep oocytes.“In common with these amino acids, alanine (2.0 microgram) also reduced LP fever and PGE2 hyperthermia.”
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