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“Overexpressed G(M)-67A (Ser-67 replaced with alanine ) exhibited decreased sensitivity to suppression of glycogen synthase activity by forskolin , while overexpression of G(M)-48A (Ser-48 replaced with alanine) preserved glycogen synthase activation in response to insulin.”
Biochemical and biophysical research communications • 2000 | View Paper
“Insulin secretion was increased by leucine+glutamine, arginine, alanine or a mixture of amino acids, but their effect was significant only in the presence of forskolin.”
“ Forskolin and fluoride also increased the glucose production from alanine and showed additive effects with glucagon, phenylephrine and phenoxybenzamine.”
Molecular and Cellular Biochemistry • 2004 | View Paper
“Incubation with forskolin (25 mumol/l) or phorbol-12-myristate 13-acetate (10 nmol/l), in the presence of L-alanine , similarly enhanced the secretory effect on BRIN-BG5 and BRIN-BG7 cells by 1.3- to 2.1-fold and 1.2- to 1.5-fold respectively.”
“ Forskolin (25 εmol/l) and phorbol 12-myristate 13-acetate (10 nmol/1) both increased insulin secretion in the presence of l-alanine (1.4- and 1.8-fold, respectively).”
“HPLC analysis of endogenous amino acids of ARM showed that glutamate, glutamine, glycine and alanine were significantly increased after forskolin stimulation.”