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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Alanine
drug:
Chlorpromazine
Research Papers that Mention the Interaction
“ Abstract Chlorpromazine ( CPZ) 1· × … alanine (25 and 3 per cent of controls respectively), the uptake of α-aminoisobutyric acid (AIB, 39 per cent of controls) and the … per cent of controls) into acid-soluble and insoluble fractions of human skin epithelial cells (HE cells, NCTC 2544) grown in culture.”
Effects of chlorpromazine and actinomycin D on uptake and incorporation of certain amino acids, hypoxanthine and thymidine in cultures of human skin epithelial cells.“In further studies, chlorpromazine (75 and 100 microM) and ouabain (0.1, 0.5, and 0.75 mM) decreased initial sodium-dependent uptake rates of taurocholate and alanine by 18-63%.”
Effects of chlorpromazine on Na+-K+-ATPase pumping and solute transport in rat hepatocytes.“ Abstract Chlorpromazine ( CPZ) and SKF 525-A above 0.01 mM inhibit the incorporation of alanine into protein in cultures of a clonal strain of rat hepatoma cells.”
“ CPZ 0.15 mM reduces the amount of total intracellularly accumulated alanine to 11 per cent of controls.”
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