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Possible Interaction: Alanine and Aspartic Acid




Aspartic Acid

Research Papers that Mention the Interaction

Exchange of aspartic acid at position 286 or 288 with alanine or asparagine decreased glucosyltransferase activity by about 5000-fold and completely blocked glucohydrolase activity.
The Journal of biological chemistry  •  1998  |  View Paper
Substitution of two aspartic acid residues with alanine at positions 54 and 59 abolished protease activity.
Molecular plant pathology  •  2011  |  View Paper
Substitution by alanine of the aspartic acid residue in the active site of both ICL domains completely abolishes their isochorismate lyase activity in vivo.
BioMetals  •  2011  |  View Paper
Substitution of this alanine residue to an aspartic acid abolished transactivation of both Myc-RP and Delila and severely reduced transactivation of Lc.
Planta  •  2007  |  View Paper
Glucose increased spore germination only slightly, regardless of pH, but enhanced germination when combined with alanine and aspartic acid.
Canadian journal of microbiology  •  1967  |  View Paper
The inhibition was competitively prevented by aspartic acid ; hence, because of the structural similarity of cysteic acid and aspartic acid, it appears that the enzyme system converting aspartic acid to fl-alanine was blocked by the inhibitor.
The Journal of biological chemistry  •  1946  |  View Paper
Substitution of the conserved aspartic acid at position 338 (TM VII) with alanine caused a loss of detectable receptor-evoked inhibition of cAMP generation, although this mutation did not appreciably affect ligand binding.
Molecular pharmacology  •  1997  |  View Paper
Conversely, for the L-isomer , a slight under-proportionality was detected in exposure with increasing doses of D ,L-MPH.
Biomedical chromatography : BMC  •  2004  |  View Paper
Whereas the folding of the mutated proteins was not seriously disrupted as judged by assembly into …, Golgi localization, and secretion of a soluble form of the enzyme, exchange of the highly conserved aspartic acid residues at position 356 … 358 with alanine or asparagine reduced enzyme activity to background levels.
Glycobiology  •  2001  |  View Paper
Substitution of aspartic acid117 and histidine260 by alanine in melanocortin 1 receptor resulted in a 4.75-fold decrease (Ki 4541 +/- 644 nM) and an 11-fold increase (Ki 84.29 +/- 4.53 nM), respectively, in the relative potency of 153N-6 for competitively inhibiting [125I]NDP-MSH binding.
Peptides  •  1996  |  View Paper
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