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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Agmatine and Spermine

supplement:

Agmatine

Research Papers that Mention the Interaction

Such cumulative results lead us to hypothesize that agmatine reduces high glucose-induced fibronectin secretion via several pathways including ERK-TGF-beta1-fibronectin and spermine , via a decrease in TGF-beta1.
Diabetes research and clinical practice  •  2004  |  View Paper
However, spermine which shares a strong nucleophilic structure with agmatine decreased the H(2)O(2) levels and AP-1, but not the NF-kappaB activity.
Journal of biochemistry and molecular biology  •  2003  |  View Paper
Moreover, spermine (an endogenous polyamine) potentiated the NMDA current even in the presence of blocker agmatine or arcaine, suggesting that the guanidine-containing compounds agmatine and arcaine interact with the NMDA channel at a binding site different from that of spermine.
The Journal of pharmacology and experimental therapeutics  •  1999  |  View Paper
Spermine and spermidine always produced a diminution in agmatine deamination.
Food microbiology  •  2008  |  View Paper