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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Agmatine and Selective Serotonin Reuptake Inhibitors

Research Papers that Mention the Interaction

These results demonstrate that modulation of imidazoline receptors by agmatine are implicated in the antidepressant like effect of SSRIs and may be projected as a potential therapeutic target for the treatment of depressive disorders.
This effect of SSRIs on agmatine levels was completely blocked by arginine decarboxylase inhibitor d-arginine but not by imidazoline receptor antagonists, efaroxan or idazoxan.
Neuropharmacology  •  2009  |  View Paper