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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Agmatine
drug:
Pimagedine
Research Papers that Mention the Interaction
“Results: Dexamethasone (2 mg/kg) and agmatine (5, 10 mg/kg) and subeffective doses of agmatine (2 mg/kg) with aminoguanidine (20 mg/kg) improved macroscopic and microscopic damage compared to acetic acid group (p < .001).”
Agmatine ameliorates acetic acid-induced colitis in rats: involvement of nitrergic system“with endogenous agmatine enhancers like l-arginine (80 μg/mouse) or arcaine (50 μg/mouse) and aminoguanidine (25 μg/mouse) restrained the development as well as expression of sensitization to EtOH.”
“In the present study, diamine oxidase inhibitor, aminoguanidine and agmatinase inhibitor, arcaine were used to block the agmatine metabolic pathways to increase brain agmatine levels.”
“ Agmatine modulation of ODC and SSAT activities is noticeably augmented by the inhibitor of its catabolism, aminoguanidine.”
“The effects of alpha-difluoromethyl-ornithine (DFMO) and aminoguanidine , which might influence the metabolism of endogenous agmatine , on pain threshold, morphine analgesia and tolerance were investigated in mice.”
“The metabolism of agmatine by DAO was inhibited by aminoguanidine (IC50 14.9 nM) and by the antidepressant, phenelzine (IC50 1.95 microM).”
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