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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Animals injected with agmatine (10–40&mgr;g/rat, icv) from day 7 to 14 before the first daily dose of nicotine (2mg/kg, sc) showed increased step through latencies during retrieval test.”
“Overall, the data indicate that agmatine attenuates nicotine withdrawal induced memory impairment through modulation of &agr;2adrenergic receptors.”
“Thus, agmatine might have therapeutic implications in the treatment of cognitive deficits following nicotine withdrawal.”
Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α2-adrenoceptors“This result clearly shows the role of agmatine in development of nicotine dependence and its withdrawal.”
“ Agmatine (20 and 40 mg/kg, ip) co-administered with nicotine during the 6 days conditioning sessions completely abolished the acquisition of nicotine-induced CPP in mice.”
“Conversely, administration of agmatine prior to the nicotine significantly reversed the effect of nicotine on NPY-immunoreactivity in the above brain nuclei.”
“This data indicate that agmatine attenuate nicotine induced CPP via modulation of NPYergic neurotransmission in brain.”
“These data indicate that agmatine attenuates nicotine induced locomotor sensitization via a mechanism which may involve alpha(2)-adrenergic receptors.”
“The present study tested whether agmatine (5-40 mg/kg, sc) modulated the locomotor, sensitizing, and discriminative stimulus effects of nicotine in male Wistar rats.”
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