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Last Updated: 4 months ago

Possible Interaction: Agmatine and Moxonidine

supplement:

Agmatine

Research Papers that Mention the Interaction

The antidepressant-like effect of agmatine in Aβ1-42 peptide in mice was potentiated by imidazoline receptor I1 agonist, moxonidine (25 µg/rat, i.c.v.)
Brain Research Bulletin  •  2020  |  View Paper
Imidazoline I1 receptor agonist, moxonidine , and I2 agonist, 2-BFI, not only decreased the development and expression of locomotor sensitization but also potentiated the effect of agmatine when employed in combination.
Alcoholism, clinical and experimental research  •  2019  |  View Paper
In combination studies, the anticompulsive-like effect of agmatine (10mg/kg, ip) was significantly potentiated by prior administration of moxonidine (0.25mg/kg, ip) or clonidine (30µg/kg,) or 2-BFI (5mg/kg, ip).
European journal of pharmacology  •  2014  |  View Paper
Both moxonidine and clonidine failed to affect carbachol or adenosine-triphosphate-induced contractions; however, 1000.0 µmol/L agmatine significantly increased these contractions.
Canadian journal of physiology and pharmacology  •  2012  |  View Paper
Similarly, the hypotension induced by moxonidine was not altered by agmatine but heart rate was reduced after the addition of agmatine (p < 0.01).
Neurochemistry International  •  1997  |  View Paper