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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Agmatine
supplement:
Guanidines
Research Papers that Mention the Interaction
“The hMATE1-mediated transport of agmatine was inhibited by polyamines, the prototypical substrates MPP+ and paraquat, as well as guanidine and arcaine, but not l-arginine.”
OCT2 and MATE1 provide bidirectional agmatine transport.“Putrescine and guanidinium ions Gdn+ ) were slope-linear, competitive inhibitors with respect to agmatine and their bindings to the enzyme were not mutually exclusive.”
Kinetic studies and site-directed mutagenesis of Escherichia coli agmatinase. A role for Glu274 in binding and correct positioning of the substrate guanidinium group.
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