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Possible Interaction: Adrenergic Beta-Antagonists and Melatonin

Research Papers that Mention the Interaction

Conclusion: These findings indicate that beta-blockers decrease melatonin release via specific inhibition of adrenergic beta1-receptors.
European Journal of Clinical Pharmacology  •  1999  |  View Paper
It is possible that by temporarily suppressing the production of melatonin , by beta-blockers for example, adaptation may be facilitated.
Temporary suppression of melatonin by beta-blockers may facilitate adaptation to phase shifts.
Neuroscience Letters  •  1998  |  View Paper
Since inhibition of melatonin secretion by beta-adrenergic blockade reduces the nocturnal decline of cBT by 40% in women, experiments were performed to investigate whether the thermoregulatory effect of light is mediated by modifications of melatonin secretion in cycling women.
The Journal of clinical endocrinology and metabolism  •  1993  |  View Paper
Beta blockers have been shown to reduce the production of melatonin via specific inhibition of adrenergic beta1-receptors.
Journal of cardiovascular disease research  •  2011  |  View Paper
beta-adrenergic blockers potently suppress melatonin production (Hanssen et al.
Biological Psychiatry  •  1986  |  View Paper
was administered one hour before lights went off (i.e. when beta blockade does not affect NST in this species) and both variables were measured for another 30 h. The beta blocker markedly augmented melatonin output of A. russatus under both photoperiod regimes.
Life sciences  •  1997  |  View Paper
It is concluded that endogenous MEL effectively protects rat PBL from adrenergic immunosuppression, and that beta-blockers enhance the immunosuppressive property of alpha 2-adrenergic agents via blocking the night-time release of MEL.
Journal of Neuroimmunology  •  1996  |  View Paper