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Last Updated: 3 years ago

Possible Interaction: Adrenergic Beta-Antagonists and Epinephrine

Research Papers that Mention the Interaction

Epinephrine has been shown to increase the DFT in the beta-blocker naïve, but using cardioselective beta-blockers leads to a reduction in the DFT on infusion of epinephrine and norepinephrine.
Heart & lung : the journal of critical care  •  2008  |  View Paper
CONCLUSIONS Administration of local anesthetic containing ep nephrine to subjects receiving a bet a-blocker in creased the duration of pulpal and soft-tissue anesthesia.
Journal of the American Dental Association  •  1999  |  View Paper
The rise in plasma adrenaline and other counter-regulatory hormones during hypoglycaemia was enhanced by beta-adrenoceptor blockade.
British journal of clinical pharmacology  •  1990  |  View Paper
Plasma noradrenalin and adrenalin increased with exercise; the increase in adrenalin with beta-blockade was greater than that with placebo (P less than 0.0001).
Clinical physiology  •  1987  |  View Paper
The hormonal concentrations demonstrated a more pronounced increase of epinephrine during beta-blockade in contrast to only small changes by norepinephrine.
Arzneimittel-Forschung  •  1985  |  View Paper
Treatment with either beta-blocking agent led to higher levels of adrenaline , glucagon, cortisol and growth hormone during hypoglycaemia as compared to those reached on placebo.
Acta endocrinologica  •  1980  |  View Paper
beta blockers, … hormone epinephrine (adrenaline), increased survival in mice with the disease.1 “We’ve been looking into this area for about 9 to 10 years,” says …, noting that the research came out of a National Cancer Institute consortium known as the Tumor Microenvironment Network, which launched in 2006.
Cancer  •  2018  |  View Paper
The effects of EPI were blocked by coinfusion of an α1‐adrenoceptor antagonist (terazosin) but not of an α2‐(atipamezole) or β1 (betaxolol)‐blocker.
Synapse  •  2003  |  View Paper
Additionally, infusion of beta-adrenergic blockers into the amygdala blocks the memory-modulating effects of epinephrine and glucocorticoids, as well as those of drugs affecting opiate and GABAergic systems.
Proceedings of the National Academy of Sciences of the United States of America  •  1996  |  View Paper
Responses to (-)-epinephrine were antagonized to a variable degree by the blockers , suggesting heterogeneous contribution of beta 1AR and beta 2AR among cells.
Circulation  •  1993  |  View Paper
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