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Last Updated: 3 years ago

Possible Interaction: Adrenergic Beta-Antagonists and Capsaicin

Research Papers that Mention the Interaction

In addition, the voltage step-evoked currents in the presence of capsaicin were inhibited by the pannexin-1 blockers in single-cell patch clamping.
Channels  •  2017  |  View Paper
Blockers of the TP receptor or TRPV1 significantly inhibited capsaicin effects, but these were still observed in the presence of 50 μM nifedipine and 70 mM KCl.
Cardiovascular research  •  2014  |  View Paper
Third, intra-articular perfusion with phentolamine (10(-5) M, an alpha-adrenoceptor antagonist), propranolol (10(-5) M, a beta-adrenoceptor antagonist ), and naloxone (10(-5) M, an opioidergic receptor antagonist) each attenuated the inhibitory action of capsaicin.
The Journal of pharmacology and experimental therapeutics  •  1999  |  View Paper
The cyclooxygenase inhibitor indomethacin, the 5-lipoxygenase inhibitor MK886 and a thromboxane A2 antagonist as well as capsaicin reduced the beta-antagonist induced contraction.
Clinical reviews in allergy & immunology  •  1996  |  View Paper
Repeated capsaicin injections, in the presence of autonomic blocking agents , caused a marked reduction in the elevation of plasma CGRP- and NKA-LI with a clear-cut fall in the bronchial vascular response, suggesting development of tachyphylaxis for local sensory mechanisms.
Acta physiologica Scandinavica. Supplementum  •  1991  |  View Paper
alpha-adrenergic blockade eliminated and beta-adrenergic blockade enhanced the increases in LCCA pressure and resistance that were evoked by capsaicin.
Journal of the autonomic nervous system  •  1988  |  View Paper