“The antinociceptive effect of the cannabinoids was also antagonized by the nonselective & agr;1 adrenoceptor antagonist prazosin, 0.5 µg/paw, 1 µg/paw, and 2 µg/paw, and by the nonselective &bgr; adrenoceptor antagonist propranolol, 150 ng/paw, 300 ng/paw, and 600 ng/paw.”