Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Adrenergic Alpha-Antagonists and Capsaicin

Research Papers that Mention the Interaction

In sympathetically intact rats, pretreatment with an alpha(1)-adrenergic receptor antagonist (terazosin) blocked completely the enhanced responses of C-fibers after CAP injection in sympathetically intact rats without significantly affecting the enhanced responses of Adelta-fibers.
Journal of neurophysiology  •  2005  |  View Paper
Third, intra-articular perfusion with phentolamine (10(-5) M, an alpha-adrenoceptor antagonist ), propranolol (10(-5) M, a beta-adrenoceptor antagonist), and naloxone (10(-5) M, an opioidergic receptor antagonist) each attenuated the inhibitory action of capsaicin.
The Journal of pharmacology and experimental therapeutics  •  1999  |  View Paper
alpha-adrenergic blockade eliminated and beta-adrenergic blockade enhanced the increases in LCCA pressure and resistance that were evoked by capsaicin.
Journal of the autonomic nervous system  •  1988  |  View Paper