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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Adenosine
drug:
Vecuronium
Research Papers that Mention the Interaction
“It was concluded that in in-vivo adenosine potentiated the neuromuscular effects of vecuronium through adenosine A1-receptors in rats.”
REVERSAL OF NEUROMUSCULAR EFFECTS OF ADENOSINE BY SPECIFIC ADENOSINE A1-RECEPTOR ANTAGONIST IN LIVE RATS“ Adenosine 0.1 mg kg-1 min-1 increased significantly maximal block induced by the ED50 of these neuromuscular blockers (55-72%, 49-73% and 60-96%, respectively, for rocuronium, vecuronium and pipecuronium; P < 0.05).”
“We conclude that adenosine potentiates neuromuscular blockade by vecuronium and that neostigmine can be expected to reverse this combined blockade.”
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