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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Adenosine
supplement:
Tubocurarine
Research Papers that Mention the Interaction
“ D‐Tubocurarine , mecamylamine, DHβE and α‐bungarotoxin, nicotinic ACh receptor antagonists, caused a concentration‐dependent reduction in the release of adenosine evoked by hypoxia.”
Activation of nicotinic ACh receptors with α4 subunits induces adenosine release at the rat carotid body“ Adenosine enhanced the inhibitory effects elicited either by tubocurarine (4 X 10(-7) - 12 X 10(-7) M), high Mg2+(5 - 11 mM) or low CA2+(0.8 - 0.3 mM) concentrations.”
“In the presence of tubocurarine , the inhibitory effects of adenosine were greater at room temperature than at 37 degrees C; however, adenosine was more potent at 37 degrees C than at room temperature in solutions with high Mg2+ or low Ca2+ concentrations.”
“The application of adenosine to rat diaphragms during steady-state partial blockade caused by flurazepam or d-tubocurarine showed an inhibiting action of adenosine which was reversed by theophylline.”
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