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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Adenosine Triphosphate and Vitamin B 12

Research Papers that Mention the Interaction

We report the dissociation constant (K(d)) of wild-type MMAB for HOCbl is 51 microM and for ATP is 365 microM and show that cobalamin enhances the affinity of MMAB for ATP , while ATP does not show detectable effects on cobalamin binding.
Molecular genetics and metabolism  •  2009  |  View Paper
In summary, vitamin B12 supplementation augments semen quality, as evidenced by values for CASA variables, antioxidant enzymes, and ATP concentrations, which may occur as a consequence of inhibition in LPO and ROS production by buffalo spermatozoa.
Animal reproduction science  •  2021  |  View Paper
In the presence of ATP , an excess of vitamin B12 promotes the reopening of the gates toward the periplasm and the dislodgment of BtuF from the transporter.
The Journal of Biological Chemistry  •  2011  |  View Paper
In BtuCD–BtuF, vitamin B12 accelerates the complex dissociation rate ∼107-fold, with ATP having an additional destabilizing effect.
Nature Structural &Molecular Biology  •  2010  |  View Paper