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Discover Supplement-Drug Interactions

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Last Updated: 2 months ago

Possible Interaction: Adenosine Triphosphate and Threonine

Research Papers that Mention the Interaction

Replacement of SS1 (C116-C165), SS2 (C126-C149) and SS4 (C217-C227), but not SS5 (C261-C270), cysteine pairs with threonines resulted in decreased sensitivity to ATP and faster deactivation times.
Physiological research  •  2010  |  View Paper
ATP stimulated dephosphorylation of MYPT1 at the inhibitory phosphorylation sites threonine 850 and 696.
Cardiovascular research  •  2007  |  View Paper
ATP also decreased threonine phosphorylation of the 65-kDa form and increased threonine phosphorylation of the 50-kDa form and tyrosine phosphorylation of the 65- and 50-kDa forms.
Endocrinology  •  2006  |  View Paper
Phosphorylation on threonine residues increased with added ATP , and it increased ATP requirements for phosphorylation on tyrosine and serine residues, suggesting a dominant-negative effect.
American journal of physiology. Cell physiology  •  2005  |  View Paper
The phosphorylation at the threonine residue also induced thick filament formation in the presence of ATP.
Biochemistry  •  1989  |  View Paper
Conclusion: The threonylcarbamoyl-AMP synthase binds l-threonine and ATP cooperatively; l-threonine is required for positioning of ATP.
The Journal of Biological Chemistry  •  2015  |  View Paper
The L‐threonine is located in a suitable position to react together with ATP for the synthesis of N6‐threonylcarbamoyladenosine.
Proteins  •  2011  |  View Paper