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Last Updated: 3 years ago
supplement:
Threonine
Research Papers that Mention the Interaction
“Replacement of SS1 (C116-C165), SS2 (C126-C149) and SS4 (C217-C227), but not SS5 (C261-C270), cysteine pairs with threonines resulted in decreased sensitivity to ATP and faster deactivation times.”
“ ATP stimulated dephosphorylation of MYPT1 at the inhibitory phosphorylation sites threonine 850 and 696.”
“ ATP also decreased threonine phosphorylation of the 65-kDa form and increased threonine phosphorylation of the 50-kDa form and tyrosine phosphorylation of the 65- and 50-kDa forms.”
“Phosphorylation on threonine residues increased with added ATP , and it increased ATP requirements for phosphorylation on tyrosine and serine residues, suggesting a dominant-negative effect.”
ATP stimulates GRK-3 phosphorylation and beta-arrestin-2-dependent internalization of P2X7 receptor.“The phosphorylation at the threonine residue also induced thick filament formation in the presence of ATP.”
Phosphorylation of a second site for myosin light chain kinase on platelet myosin.“Conclusion: The threonylcarbamoyl-AMP synthase binds l-threonine and ATP cooperatively; l-threonine is required for positioning of ATP.”
NMR-based Structural Analysis of Threonylcarbamoyl-AMP Synthase and Its Substrate Interactions*“The L‐threonine is located in a suitable position to react together with ATP for the synthesis of N6‐threonylcarbamoyladenosine.”
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