supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Thiamine
Research Papers that Mention the Interaction
“Pyruvate, ADP, thiamin pyrophosphate and dichloroacetate diminished the rate of inactivation by ATP.”
Regulation of the human pyruvate dehydrogenase complex.“ Abstract Thiamine (vitamin B1) is an essential nutrient that significantly influences ATP production in the body.”
Thiamine deficiency in a dog associated with exclusive consumption of boiled sweet potato (Ipomoea batatas): Serial changes in clinical findings, magnetic resonance imaging findings and blood lactate and thiamine concentrations“A linear relationship between the rate of thiamine transport and intracellular ATP concentration was found.”
“ATP inhibition was enhanced by NaF and reversed by high Mg++ concentrations in the absence of NaF. Pyruvate and thiamine pyrophosphate inhibited the inactivation by ATP.”
“Direct phosphorylation of thiamin with ATP , which is catalyzed by thiamin pyrophosphokinase (EC 2.7.6.2), was first demonstriited in extracts from rat liver and from brain of thiamin-deficient pigeons.’”
“Since the TCA cycle is responsible for ATP production, we hypothesized delivering vitamin B1 to mitochondria would enhance ATP production.”
Validation of the mitochondrial delivery of vitamin B1 to enhance ATP production using SH-SY5Y cells, a model neuroblast.“ Adenosine triphosphate and the ATP/ADP ratio were decreased in the hindbrain (medulla-pons area) of thiamin deficient birds (P < 0.01).”
“Since both enzyme activity and thiamin appear to be available in unimbibed soybean seeds, ATP or other nucleoside triphosphate concentration may represent an important factor in modulating thiamin phosphorylation during early seedling development.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback