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Last Updated: 4 years ago
supplement:
Serine
Research Papers that Mention the Interaction
“In this study, we examined the mechanism by which extracellular ATP triggers the release of d‐serine from astrocytes and discovered a novel Ca2+‐independent release mechanism mediated by P2X7 receptors (P2X7R).”
P2X7R‐mediated Ca2+‐independent d‐serine release via pannexin‐1 of the P2X7R‐pannexin‐1 complex in astrocytes“In the presence of 1 mM ATP , the Km for l-serine decreased from 13 mM to 1.8 mM with little change in Vmax, indicating an allosteric mechanism for nucleotide activation.”
“The results show that serine , threonine, and tyrosine residues are phosphorylated after incubation with ATP.”
“The synthesis of phosphatidyl serine was enhanced by the addition of both CTP and ATP whereas the labeling of sphingomyelin and phosphatidyl ethanolamine was little affected by these two co-factors.”
“Analyses of the transport cycle show that serine phosphorylation abolishes the K+-dependence of ATP hydrolysis and blocks the catalytic cycle after formation of the aspartyl phosphate intermediate (E1~P).”
Serine phosphorylation regulates the P-type potassium pump KdpFABC“Such anation reaction of [Cr(NH3)5(OH)]2+ with ATP subsequently leads to the esterification of alcoholic hydroxyl groups of serine and threonine of BSA.”
“The Thr197 ->Ser mutation in the yeast F1-ATPase increases the specific activity of ATP hydrolysis threefold and makes the enzyme much less sensitive to azide and oxyanions [Mueller, D. M. (1989) J. Biol.”
“Nonconservative replacement of Thr380, Thr382, or Thr384 with Ala led to inactive enzyme, whereas the conservative change to Ser caused a two to threefold reduction in ATP hydrolysis and H(+)-pumping.”
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