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Last Updated: 3 years ago
supplement:
Secretin
Research Papers that Mention the Interaction
“In the presence of guanosine 5'-triphosphate , furthermore, secretin enhanced adenylate cyclase activation in the membranes from these cells, and this activation was reduced by somatostatin, whereas neither secretin nor somatostatin affected inositol phospholipid turnover.”
“On the other hand, removal of guanosine 5'-triphosphate from incubation medium abolished both the stimulatory effect of secretin and the inhibitory effect of somatostatin on adenylate cyclase activation.”
Mechanism for increase of gastrin release by secretin in Zollinger-Ellison syndrome.“Kinetic analysis indicated that secretin and GTP increased the maximum velocity of the adenyl cyclase and tended to decrease the apparent affinity of the enzyme for ATP.”
Hormonal regulation of pancreatic islet adenyl cyclase.“ Secretin also increased the formation of cyclic AMP from ATP in homogenates of isolated fat cells.”
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