Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 months ago

Possible Interaction: Adenosine Triphosphate and Secretin

Research Papers that Mention the Interaction

In the presence of guanosine 5'-triphosphate , furthermore, secretin enhanced adenylate cyclase activation in the membranes from these cells, and this activation was reduced by somatostatin, whereas neither secretin nor somatostatin affected inositol phospholipid turnover.
On the other hand, removal of guanosine 5'-triphosphate from incubation medium abolished both the stimulatory effect of secretin and the inhibitory effect of somatostatin on adenylate cyclase activation.
Gastroenterology  •  1989  |  View Paper
Kinetic analysis indicated that secretin and GTP increased the maximum velocity of the adenyl cyclase and tended to decrease the apparent affinity of the enzyme for ATP.
Biochemistry  •  1976  |  View Paper
Secretin also increased the formation of cyclic AMP from ATP in homogenates of isolated fat cells.
Acta physiologica Scandinavica  •  1970  |  View Paper