supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Saponin
Research Papers that Mention the Interaction
“ Saponin (5 to 25 micrograms/ml) produced a concentration-dependent decrease in the cellular content of total ATP and [32P]ATP in 32P-labeled human platelets.”
ATP depletion in human platelets caused by permeabilization with saponin does not prevent serotonin secretion induced by collagen.“Removal of the endothelium by saponin and L-N(G)-nitroarginine inhibited the vasodilation induced by ATP , but indomethacin did not.”
Pharmacological analysis of responses to ATP in the isolated and perfused canine coronary artery.“The addition of increasing concentrations of ATP to ciliated cells permeabilized by exposure to saponin caused a pattern of phase reduction indistinguishable from that observed in whole cells.”
“In the presence of saponin and antimycin A, a mitochondrial inhibitor, the Ca2+ concentration in the cell suspension decreased after the addition of ATP ; the addition of inositol 1,4,5-trisphosphate (IP3) elicited transient elevations in Ca2+.”
“… saponin … ATP concentration until maximum tension (0.3-1.7 mg) was reached at about 1 mM. The sensitivity of the model to ATP was heightened … containing an ATP-regenerating system, the maximum tension (0.3-0.6 mg) being reached at 0.2 to 0.3 mM ATP.”
ATP- and calcium-controlled contraction in a saponin model of Physarum polycephalum.“The addition of ATP was not effective unless saponin was included.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback