Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Adenosine Triphosphate and Saponin

Research Papers that Mention the Interaction

Saponin (5 to 25 micrograms/ml) produced a concentration-dependent decrease in the cellular content of total ATP and [32P]ATP in 32P-labeled human platelets.
Biochemical and biophysical research communications  •  1985  |  View Paper
Removal of the endothelium by saponin and L-N(G)-nitroarginine inhibited the vasodilation induced by ATP , but indomethacin did not.
European journal of pharmacology  •  1997  |  View Paper
The addition of increasing concentrations of ATP to ciliated cells permeabilized by exposure to saponin caused a pattern of phase reduction indistinguishable from that observed in whole cells.
The American journal of physiology  •  1992  |  View Paper
In the presence of saponin and antimycin A, a mitochondrial inhibitor, the Ca2+ concentration in the cell suspension decreased after the addition of ATP ; the addition of inositol 1,4,5-trisphosphate (IP3) elicited transient elevations in Ca2+.
Endocrinology  •  1987  |  View Paper
saponin … ATP concentration until maximum tension (0.3-1.7 mg) was reached at about 1 mM. The sensitivity of the model to ATP was heightened … containing an ATP-regenerating system, the maximum tension (0.3-0.6 mg) being reached at 0.2 to 0.3 mM ATP.
Cell structure and function  •  1984  |  View Paper
The addition of ATP was not effective unless saponin was included.
Experimental cell research  •  1980  |  View Paper