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“According to changes in the kinetic parameters Vmax and Km with regard to [ATP], rutin (250 µM) increased the rate of enzyme catalysis and decreased the affinity of SERCA1 to ATP.”
British journal of pharmacology • 1995 | View Paper
“However, at concentrations of 0.2, 0.4 and 0.8 µmol/l rutin was able to inhibit high glucose-induced human mesangial cell viability, ATP content, and ACTA2 and p38 expression and improve the cell cycle progression of mesangial cells.”