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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinidine
Research Papers that Mention the Interaction
“Inhibitory effects of quinidine on the Na + -dependent phosphorylation of the enzyme complex by ATP , and the K + -stimulated breakdown of the phosphoenzyme are demonstrated.”
Effects of quinidine on some reactions and ion translocations catalyzed by the Na+, K+ -ATPase complex.“Higher concentrations of quinidine antagonized relaxations caused by ATP or non-adrenergic inhibitory nerve stimulation.”
Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non‐adrenergic inhibitory nerves in the gut“ Quinidine inhibited the ATP response and blocked the inhibitory effect of ATP on acetylcholine, potassium-depolarization and field-stimulation responses.”
“In the presence of BAY K 8644 or quinidine, ATP not only further prolonged the action potential durations by 18 +/- 4 and 17 +/- 4%, respectively, but also increased the amplitude of EADs.”
“The actions of ATP on the synaptic potentials were prevented by pretreatment with theophylline, caffeine, quinidine and 8-phenyl theophylline.”
“The excitatory actions of adenosine were blocked by the P1 receptor antagonist 8-phenyltheophylline and the excitatory effects of ATP were significantly reduced by the P2 receptor antagonist quinidine.”
“The results of this study suggest that rat ileum may contain the A1 subtype of the P1 receptor but the evidence for a P2 receptor subtype is conflicting despite the inhibition of ATP actions by quinidine.”
“The antidiuretic effect of ATP was blocked by prior injection of quinidine (a P2-purinoceptor antagonist) into the paraventricular nucleus, but not by the prior injection of theophylline (a P1-purinoceptor antagonist).”
“In the rat tail artery and the dog saphenous vein, quinidine , nordihydroguaiaretic acid (NDGA) and phentolamine inhibited the contractions induced by ATP , whereas those induced by UTP were only slightly reduced in the presence of NDGA and were not antagonized by quinidine and phentolamine.”
“ Quinidine (26-264 M) abolished the responses to ATP and acetylcholine, while indomethacin (28 microM) and theophylline (55 microM) antagonized only the acetylcholine responses.”
“ Quinidine , in the presence of adenosine‐5′‐triphosphate (ATP), inhibited the specific binding of digoxin in homogenates of heart, liver and muscle, while in the absence of ATP the inhibition was observed only in heart.”
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