supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Procaine
Research Papers that Mention the Interaction
“ p-Diethylaminoethyl benzoate (DEB) acted as a K(ATP) opener: at micromolar concentrations, it reversed the inhibitory effect of ATP and ADP, and also prevented K(ATP) rundown.”
Effects of pelargonidine and a benzocaine analogue p-diethylaminoethyl benzoate on mitochondrial K(ATP) channel.“7 45Ca2+ release induced by caffeine or β γ‐methyleneadenosine 5′‐triphosphate (AMP‐PCP) was completely inhibited by high concentrations of procaine.”
“ Procaine moderately reduced the true affinity of ATPase for ATP , whereas equilibrium binding of calcium to ATPase in the absence of ATP was virtually not modified by procaine.”
“ ATP , ADP, and AMP, but not adenosine, antagonized in a concentration‐dependent manner the antihaemolytic action of procaine , and ATP was ineffective against the antihaemolytic actions of lidocaine, dibucaine, tetracaine, pentobarbitone, and chlorpromazine.”
“ Procaine accelerated ATP hydrolysis by pre-activated thylakoid ATPase to rates which were observed in the presence of uncouplers and had no direct effect on the activation state of the ATPase.”
Detecting localized proton currents in photophosphorylation by procaine inhibition of the transthylakoid pH-gradient.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback