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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phosphatidic Acid
Research Papers that Mention the Interaction
“Similarly, depletion of ATP by dialysis reduces PA plus DG-mediated NADPH oxidase activation by approximately 70%.”
Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase.“Also, ATP synergistically stimulated DNA synthesis in combination with the direct activator of protein kinase C, phorbol myristate acetate (PMA), and with the reaction product of phospholipase D, phosphatidic acid.”
Extracellular ATP augments mesangial cell growth induced by multiple growth factors.“In fact, ATP overcame the inhibitory effects of LPA or PA on cAMP levels.”
“Lysophosphatidic acid (LPA) and phosphatidic acid PA ) inhibited adenylyl cyclase but synergized with ATP in mitogenic stimulation.”
“The mitogenic effect of ATP , but not adenosine, was further increased by lysophosphatidate, phosphatidic acid , or norepinephrine.”
“The sum of di- and triacylglycerols formed from phosphatidic acid in the presence of ATP and CoA exceeded the amount of diacylglycerol formed in their absence.”
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