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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Phenethyl Isothiocyanate
Research Papers that Mention the Interaction
“ PEITC suppressed the level of mitochondrial membrane potential; released cytochrome c from the mitochondria to the cytoplasm; reduced ATP levels; inhibited Bcl-2 expression; increased Bax expression; and activated caspase-9, caspase-3, and PARP-1, leading to apoptosis.”
Phenethyl isothiocyanate induces IPEC-J2 cells cytotoxicity and apoptosis via S-G2/M phase arrest and mitochondria-mediated Bax/Bcl-2 pathway.“ l-1 ATP protected (Na+ + K+)-ATPase activity against inhibition by BPITC.”
“…,PEITC downregulated the expression of lectin‐like oxidized low‐density lipoprotein receptor‐1 (… A1 (SR‐A1), and nuclear factor‐κB (NF‐κB), while upregulated ATP binding cassette subfamily A member 1 (ABCA1)/liver‐X‐receptor α (LXR‐… 1 (SIRT1) expression compared to co‐treated with ox‐LDL and LPS.”
Protective effects of phenethyl isothiocyanate on foam cell formation by combined treatment of oxidized low‐density lipoprotein and lipopolysaccharide in THP‐1 macrophage
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