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“Increasing concentrations (2-50 microM) of CoA (plus ATP and 20 microM added palmitic acid ) or of palmitoyl-CoA progressively decreased glucose-6-phosphatase activity to 50% of the control value.”
“When [3H]palmitic acid was used as precursor in the presence of both ATP and CoA, esterification of myelin PLP occurred rapidly in adult animals, indicating that both nonacylated PLP and acyl-CoA ligase are present in myelin.”
“It is suggested that palmitic acid and gramicidin D interfere with a direct H+ transfer between specific electron transport and the ATP synthase complexes, which provides an alternative coupling mechanism in parallel with bulk to bulk delta microH+.”