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Last Updated: 3 years ago

Possible Interaction: Adenosine Triphosphate and Manganese Cation (2+)

drug:

Adenosine Triphosphate

supplement:

Manganese Cation (2+)

Research Papers that Mention the Interaction

“Cell viability and ATP levels both decreased at the highest Mn(II) and Mn(III) exposures (150-200 microM), while Mn(III) exposures produced increases in LDH activity at lower exposures (> or =50 microM) than did Mn(II) (200 microM only).”

Manganese oxidation state mediates toxicity in PC12 cells.

Toxicology and applied pharmacology • 2005 | View Paper

“The oxidative inactivation promoted by ATP is inhibited by Mg2+, Mn2+ , catalase, and EDTA, is not mediated by dehydroascorbate, and is not associated with oxidation of cysteines 1327 and 1337.”

Oxidative inactivation of carbamoyl phosphate synthetase (ammonia). Mechanism and sites of oxidation, degradation of the oxidized enzyme, and inactivation by glycerol, EDTA, and thiol protecting agents.

The Journal of biological chemistry • 1992 | View Paper

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Possible Interaction: Adenosine Triphosphate and Manganese Cation (2+)

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Adenosine Triphosphate

Manganese Cation (2+)

Research Papers that Mention the Interaction