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“Our results show that the concentration of magnesium ion influences the potency of adenosine triphosphate (ATP) competitive inhibitors, suggesting an explanation for the observation that such compounds retain their nanomolar potency in cells despite the presence of millimolar levels of ATP.”
Journal of enzyme inhibition and medicinal chemistry • 2012 | View Paper
“When ATP (1 mM) and Mg2+ (2 mM) were added together and a depolarizing potential was simultaneously applied, only a high-conductance channel (about 75 pS) was observed.”
“Calcium and magnesium ions inhibited the hydrolysis of ATP and PP1 and evidence is presented to show that the metal complexes of these substrates are not hydrolysed by alkaline phosphatase.”
Canadian journal of biochemistry • 1979 | View Paper
“It is known for a long time, that Mg++ forms a complex with ATP (MARTELL et al.,1956) and in 1970 it was found, that DPG forms also a complex with Mg++ (COLLIER et al.).”
Advances in experimental medicine and biology • 1976 | View Paper
“This may indicate that magnesium ions stimulate deficient ATPase activity and lead to diminution of ATP as a negative effector for other regulatory enzymes.”
The Journal of Membrane Biology • 2005 | View Paper
“UDP did not alter the binding … m M. In the presence of Mg2+ (20 m … effects of ATP (0.01–1 m M) or ADP (0.01–5 m M) on the binding in … were abolished, whereas the facilitatory effects of ATP or ADP in aortic preparations were strengthened.”
Journal of cardiovascular pharmacology • 2001 | View Paper
“Furthermore, it was found that the presence of magnesium ions during preincubation weakened the up-regulatory effect of ATP (2.5mM) on BA-N1-oxidation, but showed no effect on the down-regulatory effect of ATP (20mM).”