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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Linoleic Acid
Research Papers that Mention the Interaction
“At less than 0.15 mM ATP, linoleic acid stimulated NaK-ATPase, but at higher ATP concentrations, the enzyme was progressively inhibited.”
Identification of NaK-ATPase inhibitors in human plasma as nonesterified fatty acids and lysophospholipids.“In addition, OA and LA rapidly decreased sustained increase in [Ca2+]i induced by ATP AS when OA or LA was added after stimulation with ATP AS.”
“OA and LA inhibited ATP AS-induced Ca2+ release from intracellular Ca2+ stores and increase in Ca2+ influx from extracellular space.”
Unsaturated free fatty acids inhibit Ca2+ mobilization and NO release in endothelial cells.“255, 10566-10568) in a recent paper argued, however, that linoleic acid causes depletion of ATP , as measured by the luciferin/luciferase assay, and respiratory uncoupling.”
“ Linoleic acid produces artifacts in ATP measurements made using the luciferin/luciferase assay which leads to an erroneous conclusion regarding the ATP dependence of the capping inhibition.”
“In the mitochondria of stressed cells, PUMP activity increased by approximately 45% (at 24h and 48 h), which was determined by measuring the oxygen consumption after the addition of linoleic acid and the inhibition by BSA and ATP.”
The involvement of PUMP from mitochondria of Araucaria angustifolia embryogenic cells in response to cold stress.
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