Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Adenosine Triphosphate and Linoleic Acid

Research Papers that Mention the Interaction

At less than 0.15 mM ATP, linoleic acid stimulated NaK-ATPase, but at higher ATP concentrations, the enzyme was progressively inhibited.
The Journal of biological chemistry  •  1986  |  View Paper
In addition, OA and LA rapidly decreased sustained increase in [Ca2+]i induced by ATP AS when OA or LA was added after stimulation with ATP AS.
OA and LA inhibited ATP AS-induced Ca2+ release from intracellular Ca2+ stores and increase in Ca2+ influx from extracellular space.
The Kobe journal of medical sciences  •  2001  |  View Paper
255, 10566-10568) in a recent paper argued, however, that linoleic acid causes depletion of ATP , as measured by the luciferin/luciferase assay, and respiratory uncoupling.
Linoleic acid produces artifacts in ATP measurements made using the luciferin/luciferase assay which leads to an erroneous conclusion regarding the ATP dependence of the capping inhibition.
The Journal of biological chemistry  •  1982  |  View Paper
In the mitochondria of stressed cells, PUMP activity increased by approximately 45% (at 24h and 48 h), which was determined by measuring the oxygen consumption after the addition of linoleic acid and the inhibition by BSA and ATP.
Plant science : an international journal of experimental plant biology  •  2012  |  View Paper