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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Levocarnitine
Research Papers that Mention the Interaction
“ L-carnitine significantly increased ATP levels in 2-cell embryos but not at the 8-cell or blastocyst stages.”
Supplementation of culture medium with L-carnitine improves development and cryotolerance of bovine embryos produced in vitro.“Treatment of C2C12 cells with 1 mmol/l of ATP induced a marked increase in L-carnitine uptake that was associated with an increase in L-carnitine content in these cells.”
“Since LC maintains the ATP/ADP ratio and was previously shown to be neuroprotective against 3-NPA toxicity, the modulation of UCP-2 expression by LC suggests that LC counteracts energy dissipation and thus prevents the negative effects of ATP decline on DA neurotransmission.”
“Increased pyruvate kinase activity is associated with stimulation of ATP synthesis in the presence of L-carnitine.”
“Pretreatment of L-carnitine prevented the decrease in free carnitine and ATP and the increase in long-chain acyl carnitine and long-chain acyl CoA. A positive correlation was observed between ATP and free carnitine.”
“ ATP in the ischemic myocardium in the L-carnitine group was significantly higher than that in the control group (p less than 0.05).”
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